| STX-0119 |
Influence on tumor growth |
Tumor volume |
40.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
|
|
| STX-0119 |
Influence on tumor growth |
Tumor volume |
160.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
|
|
| STX-0119 |
Influence on tumor growth |
Body weight |
40.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
|
|
| STX-0119 |
Influence on tumor growth |
Body weight |
160.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
|
|
| STX-0119 |
Influence on protein activity in tumor tissue |
Western Blot |
80.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
p-STAT3 |
|
| STX-0119 |
Influence on protein activity in tumor tissue |
Western Blot |
160.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
p-STAT3 |
|
| STX-0119 |
Influence on protein activity in tumor tissue |
Western Blot |
80.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
STAT3 |
|
| STX-0119 |
Influence on protein activity in tumor tissue |
Western Blot |
160.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
STAT3 |
|
| STX-0119 |
Influence on dowstream target genes expression in tumor tissue |
Western Blot |
80.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
|
|
| STX-0119 |
Influence on dowstream target genes expression in tumor tissue |
Western Blot |
160.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
|
|
| STX-0119 |
Influence on dowstream target genes expression in tumor tissue |
Western Blot |
80.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
|
|
| STX-0119 |
Influence on dowstream target genes expression in tumor tissue |
Western Blot |
160.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
|
|
| STX-0119 |
Influence on dowstream target genes expression in tumor tissue |
Western Blot |
80.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
|
|
| STX-0119 |
Influence on dowstream target genes expression in tumor tissue |
Western Blot |
160.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
|
|
| STX-0119 |
Influence on dowstream target genes expression in tumor tissue |
Western Blot |
80.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
|
|
| STX-0119 |
Influence on dowstream target genes expression in tumor tissue |
Western Blot |
160.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
|
|
| STX-0119 |
Influence on protein activity in tumor tissue |
Hematoxylin and eosin staining |
160.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
|
|
| STX-0119 |
Influence on protein activity in tumor tissue |
Immunostaining |
160.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
|
|
| STX-0119 |
Influence on protein activity in tumor tissue |
Immunostaining |
160.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
|
|
| STX-0119 |
Influence on protein activity in tumor tissue |
Immunostaining |
160.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
p-STAT3 |
|
| STX-0119 |
Influence on protein activity in tumor tissue |
Immunostaining |
160.00 mg/kg |
SCC3 (xenograft) |
Mus musculus |
BALB/cA-nu/nu |
STAT3 |
|
| STX-0119 |
Influence on artery contractility in precence of IFNγLPS and noradrenaline |
Constriction assay |
10.00 nM |
mesenteric artery |
Mus musculus |
|
|
|
